Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox checked   Rule 13d-1(c)
Checkbox not checked   Rule 13d-1(d)






SCHEDULE 13G




Comment for Type of Reporting Person:  These securities are held of record by TCG Crossover II (as defined in Item 2(a) below) and consists of (i) 13,135,260 shares of Common Stock and (ii) 57,850 shares of Common Stock subject to pre-funded warrants (the Pre-Funded Warrants). This total excludes 10,334,890 shares of Common Stock subject to the Pre-Funded Warrants not exercisable within 60 days of this Statement because the Pre-Funded Warrants may not be exercised to the extent that doing so would result in the holder of the Pre-Funded Warrants (together with the holder's affiliates and any other persons acting as a group together with the holder or any of the holder's affiliates) beneficially owning more than 9.99 percent of the shares of Common Stock then outstanding immediately after giving effect to such exercise (the Beneficial Ownership Limitation). TCG Crossover GP II (as defined in Item 2(a) below) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities. The amount beneficially owned by each Reporting Person (as defined in Item 2(a) below) is determined based on 132,064,678 shares of Common Stock, which is the sum of (i) 132,006,828 shares of Common Stock outstanding as of December 27, 2024 as reported by the Issuer to the Reporting Persons, plus (ii) 57,850 shares of Common Stock issuable upon the exercise of Pre-Funded Warrants.


SCHEDULE 13G




Comment for Type of Reporting Person:  These securities are held of record by TCG Crossover II and consists of (i) 13,135,260 shares of Common Stock and (ii) 57,850 shares of Common Stock subject to the Pre-Funded Warrants. This total excludes 10,334,890 shares of Common Stock subject to the Pre-Funded Warrants not exercisable within 60 days of this Statement because of the Beneficial Ownership Limitation. TCG Crossover GP II is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities. The amount beneficially owned by each Reporting Person is determined based on 132,064,678 shares of Common Stock, which is the sum of (i) 132,006,828 shares of Common Stock outstanding as of December 27, 2024 as reported by the Issuer to the Reporting Persons, plus (ii) 57,850 shares of Common Stock issuable upon the exercise of Pre-Funded Warrants.


SCHEDULE 13G




Comment for Type of Reporting Person:  These securities are held of record by TCG Crossover II and consists of (i) 13,135,260 shares of Common Stock and (ii) 57,850 shares of Common Stock subject to the Pre-Funded Warrants. This total excludes 10,334,890 shares of Common Stock subject to the Pre-Funded Warrants not exercisable within 60 days of this Statement because of the Beneficial Ownership Limitation. TCG Crossover GP II is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities. The amount beneficially owned by each Reporting Person is determined based on 132,064,678 shares of Common Stock, which is the sum of (i) 132,006,828 shares of Common Stock outstanding as of December 27, 2024 as reported by the Issuer to the Reporting Persons, plus (ii) 57,850 shares of Common Stock issuable upon the exercise of Pre-Funded Warrants.


SCHEDULE 13G



 
TCG Crossover GP II, LLC
 
Signature:/s/ Craig Skaling
Name/Title:Authorized Signatory
Date:01/03/2025
 
TCG Crossover Fund II, L.P.
 
Signature:/s/ Craig Skaling
Name/Title:Authorized Signatory
Date:01/03/2025
 
Chen Yu
 
Signature:/s/ Craig Skaling
Name/Title:By POA as Attorney-in-Fact
Date:01/03/2025
Exhibit Information

Material to be Filed as Exhibits. Exhibit 1 - Joint Filing Agreement.